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Read What Our Customers Say About Crystal Shifter

“Wright and colleagues showed that the Shifter significantly reduces evaporation compared with film cutting and resealing, lowering stress on the crystals and extending the time available for mounting before the drop dries.
[...]
Mounted crystals that yielded diffraction datasets in the Shifter experiments showed a significant improvement in mounting success compared with the manual process.”
Click here to read more in IUCr Acta Cryst. (2021)
IUCr Acta Crys, 2021's logo
Wright, et al.IUCr Acta Crys, 2021
“Harvesting crystals from 96 well plates is always stressful, the drops are drying out quite fast while the crystal quality deteriorates with the same pace.
Using the Crystal Shifter makes crystal fishing easier and more successful. The lifetime of each drop increases dramatically, allowing to fish more and better diffracting crystals.
The built-in soaking protocols are very helpful for my project that is related to inhibitor screening. The software is user friendly and the fact that you can so easily document all your work is invaluable.”
DESY MX's logo
Dr Spyros ChatziefthymiouDESY MX
“The Crystal Shifter is a workhorse instrument in the XChem facility at Diamond Light Source. It has been key for enabling high-throughput crystallographic fragment screening by significantly improving efficiencies in sample preparation and preserving metadata across an experiment.
Many of our users have introduced Shifters into their own lab workflows following XChem experiments such is the obvious impact of their benefits.”
XChem, Diamond Light Source's logo
Dr Daren FearonXChem, Diamond Light Source
“I've used the Crystal Shifter for the past three years. It simplifies crystal manipulation, significantly boosting productivity.
It's perfectly suited for fragment or compound screening campaigns, as well as for more complex and delicate crystal manipulations.
With intuitive controls and software, it streamlines complex lab processes, offering an efficient and seamless user experience for researchers of all skill levels.”
Senior Scientist's logo
Dr Leo SilvestreSenior Scientist
“We love using the Crystal Shifter to greatly accelerate crystal harvesting for high-throughput X-ray crystallography.
It allows us to ask scientific questions, at scale, which we couldn't do without it! ”
QB3 UCSF's logo
Prof James FraserQB3 UCSF
“By the 24th of March, the initial 1500-crystal experiment was complete, and the results made publicly available… This was an exceptionally large screen which yielded a remarkably rich readout, with vast opportunities for fragment growing and merging.”
Diamond Light Source's logo
XChem LabDiamond Light Source
“We do a lot of co-crystallization experiments as well as screening for new crystal forms. The Crystal Shifter® is an essential part of our high-throughput crystallography set-up, allowing us to mount and record the data for hundreds of crystals per day. I honestly don't know how we would cope without it. ”
Centre for Medicines Discovery (Oxford)'s logo
Dr Lizbé KoekemoerCentre for Medicines Discovery (Oxford)

Our Customers

Our customers: top pharmaceutical FBDD drug discovery labs
Our customers: academic research and beamline synchrotron labs